Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005
Identifieur interne : 001E00 ( Main/Exploration ); précédent : 001D99; suivant : 001E01Middle East Respiratory Syndrome Coronavirus Antibody Reactors Among Camels in Dubai, United Arab Emirates, in 2005
Auteurs : S. Alexandersen [Canada] ; G. P. Kobinger [Canada] ; G. Soule [Canada] ; U. Wernery [Émirats arabes unis]Source :
- Transboundary and Emerging Diseases [ 1865-1674 ] ; 2014-04.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Chameaux (virologie), Coronavirus (immunologie), Coronavirus (isolement et purification), Equus caballus, Incidence, Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Moyen Orient, Ovis, Syndrome, Tests de neutralisation, Émirats arabes unis (épidémiologie).
- MESH :
- immunologie : Coronavirus.
- isolement et purification : Coronavirus.
- médecine vétérinaire : Infections à coronavirus.
- sang : Anticorps antiviraux.
- virologie : Chameaux, Infections à coronavirus.
- épidémiologie : Infections à coronavirus, Émirats arabes unis.
- Animaux, Equus caballus, Incidence, Moyen Orient, Ovis, Syndrome, Tests de neutralisation.
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Camelus (virology), Coronavirus (immunology), Coronavirus (isolation & purification), Coronavirus Infections (epidemiology), Coronavirus Infections (veterinary), Coronavirus Infections (virology), Horses, Incidence, Middle East, Neutralization Tests, Sheep, Syndrome, United Arab Emirates (epidemiology).
- MESH :
- chemical , blood : Antibodies, Viral.
- epidemiology : Coronavirus Infections, United Arab Emirates.
- immunology : Coronavirus.
- isolation & purification : Coronavirus.
- veterinary : Coronavirus Infections.
- virology : Camelus, Coronavirus Infections.
- Animals, Horses, Incidence, Middle East, Neutralization Tests, Sheep, Syndrome.
Abstract
We tested, using a low starting dilution, sequential serum samples from dromedary camels, sheep and horses collected in Dubai from February/April to October of 2005 and from dromedary camels for export/import testing between Canada and USA in 2000–2001. Using a standard Middle East respiratory syndrome coronavirus (MERS‐CoV) neutralization test, serial sera from three sheep and three horses were all negative while sera from 9 of 11 dromedary camels from Dubai were positive for antibodies supported by similar results in a MERS‐CoV recombinant partial spike protein antibody ELISA. The two negative Dubai camels were both dromedary calves and remained negative over the 5 months studied. The six dromedary samples from USA and Canada were negative in both tests. These results support the recent findings that infection with MERS‐CoV or a closely related virus is not a new occurrence in camels in the Middle East. Therefore, interactions of MERS‐CoV at the human–animal interface may have been ongoing for several, perhaps many, years and by inference, a widespread pandemic may be less likely unless significant evolution of the virus allow accelerated infection and spread potential in the human population.
Url:
- https://api.istex.fr/ark:/67375/WNG-FB6NHQCJ-R/fulltext.pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282458
DOI: 10.1111/tbed.12212
Affiliations:
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Le document en format XML
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Soule</name><affiliation wicri:level="1"><country xml:lang="fr">Canada</country><wicri:regionArea>National Microbiology Laboratory (NML), Public Health Agency of Canada, Canadian Science Centre for Human and Animal Health, MB, Winnipeg</wicri:regionArea><wicri:noRegion>Winnipeg</wicri:noRegion></affiliation></author><author><name sortKey="Wernery, U" sort="Wernery, U" uniqKey="Wernery U" first="U." last="Wernery">U. 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Using a standard Middle East respiratory syndrome coronavirus (MERS‐CoV) neutralization test, serial sera from three sheep and three horses were all negative while sera from 9 of 11 dromedary camels from Dubai were positive for antibodies supported by similar results in a MERS‐CoV recombinant partial spike protein antibody ELISA. The two negative Dubai camels were both dromedary calves and remained negative over the 5 months studied. The six dromedary samples from USA and Canada were negative in both tests. These results support the recent findings that infection with MERS‐CoV or a closely related virus is not a new occurrence in camels in the Middle East. Therefore, interactions of MERS‐CoV at the human–animal interface may have been ongoing for several, perhaps many, years and by inference, a widespread pandemic may be less likely unless significant evolution of the virus allow accelerated infection and spread potential in the human population.</div></front></TEI><affiliations><list><country><li>Canada</li><li>Émirats arabes unis</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Alexandersen, S" sort="Alexandersen, S" uniqKey="Alexandersen S" first="S." last="Alexandersen">S. Alexandersen</name></noRegion><name sortKey="Alexandersen, S" sort="Alexandersen, S" uniqKey="Alexandersen S" first="S." last="Alexandersen">S. Alexandersen</name><name sortKey="Kobinger, G P" sort="Kobinger, G P" uniqKey="Kobinger G" first="G. P." last="Kobinger">G. P. Kobinger</name><name sortKey="Soule, G" sort="Soule, G" uniqKey="Soule G" first="G." last="Soule">G. Soule</name></country><country name="Émirats arabes unis"><noRegion><name sortKey="Wernery, U" sort="Wernery, U" uniqKey="Wernery U" first="U." last="Wernery">U. Wernery</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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